Transcription factors are proteins that regulate the transcription of genes—their copying into RNA on the way to making a protein. The function of TFs is to regulate genes to ensure that they are expressed in the desired cells at the right time and in the right amount throughout the life of the cell and the organism. LncRNAs can interact with transcription factors to regulate gene transcription. The lncRNAs can be nuclear, nucleolar, or cytoplasmic or occupy several cellular compartments. The cellular localization of a lncRNA is informative regarding its function.

Fig. 1 Diagram of the role of transcription factors.

Lifeasible provides analysis services for plant lncRNA that control the transcription factors to help our customers worldwide in plant science research. Our platform is equipped with cutting-edge facilities and professional experts to support research. Here, we provide various services according to customers' demands.

Regulating Transcription Factor Activity

• LncRNA can interact with transcription factors to regulate gene transcription. They can recruit transcriptional regulators to the promoter regions of target genes to regulate target gene transcription.
• We help customers analyze the role of plant lncRNA in regulating transcription factors. Some lncRNAs may function at the RNA level, such as ribozymes or riboswitches. Most commonly, however, lncRNAs perform their functions as ribonucleoprotein particles (RNPs).
• We also help customers analyze the role of plant lncRNA in regulating transcription factor activity. lncRNA also regulates the activity of transcription factors. Some lncRNA can form transcriptional complexes with transcription factors, thus enhancing or attenuating the expression of transcription factors.

Regulating Transcription Factors Modes

• Generally, several ways lncRNAs can regulate transcription are as follows, recruitment, inhibition, the act of transcription indirectly, the genome organization, and the architecture of the nucleus indirectly.
• We provide an analysis of the modes of transcription factors regulated by plant lncRNAs. RNA can recruit a regulatory protein complex to a gene or an entire chromosome in cis or trans. Transcription of a lncRNA may regulate the transcription of nearby mRNA genes, either positively or negatively. Conversely, RNA can inhibit the binding of a transcriptional regulatory factor by acting as a "decoy" or inhibit its activity by direct active-site occlusion, by allosteric effects, or more indirectly.

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