Plant Epigenetics

Epigenetic analysis at the methylation level

We can provide you with restriction endonuclease-based DNA methylation assays, bisulfite-based DNA methylation assays, immunoprecipitation of methylated DNA, direct detection of DNA methylation by SMRT sequencing, and single-molecule nanopore-dependent methylation sequencing, etc. Moreover, we have reasonable solutions for RNA methylation, RNA-directed DNA methylation, and DNA hydroxymethylation.

Epigenetic analysis at the histone level

We provide technical services on histone variants, histone chaperones, and histone arginine methylation, which can provide you with new ideas for molecular biology, genetics, and evolutionary biology. In addition, we have newly introduced the services of histone methyltransferases (HMTs) activity or inhibition analysis assays and histone demethylase activity or inhibition assays.

Epigenetic analysis at the chromatin level

We provide you with a chromatin remodeling service parsing service and various technical tools to help you with chromatin analysis, including DNase-seq, MNase-seq, ATAC-seq, NOMe-seq, FAIRE-seq, and so on.

Epigenetic analysis at the RNA level

We can provide you with epigenetic analysis services at the RNA level from various aspects, including small RNAs, non-coding RNAs, and miRNAs. Includes small RNA regulatory analysis, small RNA library analysis, non-coding RNA gene identification, the theoretical prediction of non-coding RNA genes, microRNA detection, small interfering RNA analysis, and RNA modification detection.

Analysis of epigenetic molecular mechanisms

Our extensive epigenetic research tools, including but not limited to single-cell methylome and oxidative bisulfite sequencing, allow you to elucidate and newly interpret a growing number of epigenetic molecular mechanisms and new interpretations. These include transposable factor analysis, synthesis of plant artificial chromosomes, epigenetically related gene expression assays, gene imprinting analyses, and construction of epigenome maps.

Epigenetic of plant centromere

We provide services such as mitotic DNA sequence cloning and isolation. We can provide you with a complete assembly of centromere, telomeric repeat cluster tagging, centromere array tagging, and cytogenetic validation of chromosome-specific satellites using FISH for cytogenetic validation of centromere according to your needs for comprehensive analysis of the genetic, structural, and functional, and epigenetic characteristics of centromere.

Epigenetic editing breeding techniques

We provide you with epigenetic editing and breeding techniques with universal applicability for breeding high-yielding and high-biomass superior varieties to increase food production. In addition, we are trying to apply CRISPR/Cas9 technology to RNA mutations and modifications so that you can explore acquired genetics, translational regulation of proteins, and viral detection of RNA to support the exploration of gene function and life science research.

Epigenetic of plant polyploidy

We use techniques such as population genetics and multi-omics analysis to identify epigenetic loci associated with important agronomic traits in polyploid crops. We are also available to meet your needs for further crop improvement through artificial design and epigenetic breeding and to explore the creation of new polyploid species.