Analysis of Plant lncRNA Regulating Immunity

To overcome the challenges of severe environmental conditions, such as an endless barrage of pathogens and pests, plants have developed complex immune systems to recognize stressors and generate appropriate signals to regulate growth and development. Long non-coding RNAs (lncRNAs) refer to RNAs with a length of more than 200 nt and usually do not have protein-coding functions and do not belong to any other well-known non-coding RNA types. Emerging studies have shown that plants employ lncRNAs to regulate plant immunity.

LncRNAs in plant immunity. Fig. 1 LncRNAs in plant immunity. (Huang J, et al., 2023)

Lifeasible, as a leading global company, is committed to helping our customers achieve effective and successful research. We provide analysis services of plant lncRNA in regulating immunity, mainly including the immune perception process, immune response, and plant-microbe/insect interactions. In addition, we deliver reliable results and reports on time to our customers worldwide.

Analysis of Plant lncRNA in Immune Perception Processes

  • Plants employ numerous cell-surface and intracellular immune receptors to perceive various immunogenic signals associated with pathogen infection and subsequently activate defenses.
  • We help clients analyze the role of plant lncRNA in the immune perception process, including nucleotide-binding domain leucine-rich repeat (NLR)-recognized and pattern recognition receptor (PRR)-recognized immunogenic signals. LncRNAs have also been shown to be differentially expressed, corresponding to the activation of NLRs and PRRs.

Analysis of Plant lncRNA in Immune Response

  • Plants have evolved highly complex pathogen defense systems, which function in a manner like the innate immune systems of humans. These immune responses are fine-tuned not only by protein-coding genes but also by lncRNAs.
  • We offer analysis services for plant lncRNA in the immune response, including ROS accumulation, calcium influx, MAPK cascades activation, altering the defense-related gene expression, and hormones and hormone pathways. Among them, defense-related genes involve pathogenesis-related (PR), lipoxygenase (LOX), phenylalanine ammonia-lyase (PAL), catalase (CAT), GDSL lipase, antimicrobial peptides (AMPs), etc.

Analysis of Plant lncRNA in Plant-Microbe/Insect Interactions

  • In natural ecosystems, plants interact with biotic components such as microbes, insects, animals, and other plants. Therefore, plants have evolved defense mechanisms to mitigate different diseases effectively.
  • We offer analysis services for plant lncRNA in the interactions of plant-microbe/insect, including plant-virus, plant-fungi, plant-bacteria, plant-oomycete, and plant-insect interactions. In our service lists, plant-fungi interactions include Fusarium oxysporum, powdery mildew, stripe rust, Sclerotinia sclerotiorum, plant-bacteria interactions involve Pseudomonas syringae, Ralstonia solanacearum infections, and plant-insect interactions cover armyworms, whitefly, and aphid.

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Reference

  1. Huang J, et al. (2023). "Roles of long non-coding RNAs in plant immunity." PLoS Pathog. 19 (5), e1011340.

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