Natural Drug Development

Natural drugs are drugs developed from natural resources such as plants, animals, and microorganisms, and are an important part of medicines. Natural drugs have a long history of medicinal use, and the active compounds they contain are an important source of lead structures in drug discovery research. With the progress of life science and the continuous elucidation of the body's own function regulation system, many endogenous physiologically active substances are also being uncovered. On this basis, Lifeasible is conducting extensive screening using new bioactive testing systems established at the molecular level to discover more and newer natural drugs.

Our Solution

The development of new drugs of plant origin is a very complex and highly technology-intensive system engineering, involving many disciplines such as chemistry, pharmacology, formulation, clinical medicine, and toxicology. The development of a new class of drugs from natural drug active ingredients is a time-consuming and labor-intensive long-term process, and our experts have the experience and professional research background to provide you with technical guidance and optimization of programs and processes.

• Collect raw materials for activity screening, isolate and trace active ingredients, and confirm structures.
• Conduct efficacy tests, toxicity tests (including acute toxicity tests, long-term toxicity tests, special toxicity tests, i.e., teratogenic, carcinogenic, mutagenic, dependence tests, etc.), and pharmacokinetic tests.
• Conduct raw material supply assurance research (i.e., resource survey, cultivation research, tissue culture, and artificial synthesis).
• Formulation industrialization research (i.e., prescription and process research, clinical and manufacturing drug quality research, raw material and formulation stability research, and bioavailability or dissolution testing).
• Clinical research, after clinical trials in Phase I (initiation phase) and Phase II (controlled treatment trial phase), followed by trial production and Phase III (safety study phase) clinical trials.

Effective solutions to resource problems in drug development derived from structurally complex natural products

• Finding abundant natural precursors and preparing them by biosynthesis
• Preparation by chemical transformation of abundant natural analogs
• Simplify the structure of the precursor and prepare it by total synthesis

Our Focus

• General activity studies for extraction and isolation, structure identification to elucidate medicinal bioactive ingredients to obtain compounds with new structures or monomers with biological activity.
• Semi-synthetic and biotransformation studies to solve the source of active compounds or their precursors with limited natural resources.
• To obtain efficient and innovative drugs, a series of structural analogs are synthesized for conformational studies using natural active compounds as precursors.

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For research or industrial use.

Related Solutions

• Plant Origin Active Substance