Post-transcriptional regulation refers to regulating gene expression after RNA transcription and is a characteristic of eukaryotic gene expression. The primary transcript formed after transcription must undergo a series of processes before transforming into a functional mature mRNA, which serves as a template for protein translation. Besides the transcriptional regulation of lncRNAs, shared with that of host genes or controlled independently, evidence is mounting that lncRNAs are also regulated post-transcriptionally.

Fig. 1 Overview of the post-transcriptional modification of pre-mRNA.

Lifeasible, as a leading global company, is committed to helping our customers achieve effective and successful research. We provide analysis services of plant lncRNA in post-transcriptional regulation, including plant lncRNA-mediated RNA degradation, plant lncRNA in alternative splicing regulation, and RNA stability regulation. In addition, we deliver reliable results and reports on time to our customers worldwide.

Analysis of Plant lncRNA in Alternative Splicing Regulation

• Most eukaryotic genes transcribe mRNA precursors that are spliced in one way; they produce one mature mRNA molecule and thus translate into only one protein. However, some genes produce different mRNA splice isoforms by splicing one mRNA precursor in different ways (selecting various splice sites), a process called variable splicing (or alternative splicing).
• We help clients analyze the plant lncRNA involved in regulating variable splicing, including interacting with splicing factors, regulating splicing through chromatin remodeling, and lncRNA-RNA duplexes. Our technical team will make a suitable solution according to the purpose of our client's research.

Analysis of Plant lncRNA-Mediated RNA Degradation

• RNA degradation in eukaryotic cells is a crucial modulator of gene expression, as it counterbalances the transcription rate and rapidly eliminates transcripts when they are no longer needed.
• We provide analysis services for plant lncRNA-mediated RNA degradation. lncRNA can mediate the degradation of mRNA, and the abundance of mRNA directly affects the protein yield. One of the critical pathways mediating mRNA degradation is nonsense-mediated mRNA degradation.

Analysis of Plant lncRNA in RNA Stability Regulation

• RNA stabilities refer to the extent to which an RNA molecule retains its structural integrity and resists degradation under changing in vivo or in vitro conditions. They are measured by the decrease in RNA over time after inhibiting RNA transcription.
• We help our customers analyze the role of plant lncRNA in regulating RNA stability, including inducing miRNA blockage, interacting with RNA-binding proteins, and being involved in epi-transcriptomic changes. Plant lncRNA is emerging as a prominent regulator of mRNA stability and decay.

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Related Services

• Analysis of Plant lncRNA in Pre-Transcriptional Regulation
• Analysis of Plant lncRNA in Transcriptional Regulation