Actinomycetes are important producers of bioactive metabolites, including antibiotics, plant growth factors, enzyme inhibitors, and many other beneficial compounds. Extreme alpine habitats of hypothermia, hypoxia, and stress-adapted plants, as well as inter-root soils, may contain novel strains of actinomycetes with unique metabolic profiles and new secondary metabolites. Actinomycetes can produce various bioactive substances such as antibiotics, enzymes, and their inhibitors. Most of the antibiotics currently in use are derived from actinomycetes, which have great application in agricultural and forestry production and clinical medicine.

What We Offer

Lifeasible provides services for the isolation, identification, population diversity, and bioactivity of interplant root actinomycetes from various medicinal plants, some habitat-specific plants, and model plants such as tobacco.

The combination of different pretreatment methods and media has different isolation effects, and the drying and heating of natural samples can better screen for rare actinomycetes. Some rare actinomycetes have broad-spectrum resistance to antibiotics, so we also select selective media containing antibiotic drugs to inhibit bacteria and those fast-growing actinomycetes. In addition, we also use phenol treatment, calcium carbonate treatment, and microwave radiation to improve the yield of rare actinomycetes.

Endophytic microorganisms and plants continuously exchange material, energy, and genetic information during the long-term evolutionary process, and endophytic bacteria and host plants eventually form a relatively stable ecological relationship, so that microorganisms within the plant may produce compounds similar to those of the plant. In contrast, inter-rhizosphere microorganisms, which have been influenced by plant root secretions for a long time, produce antimicrobial substances at a significantly higher rate than non-inter-rhizosphere microorganisms. Lifeasible provides analytical services for various plant inter-rhizosphere actinomycetes, starting with selective isolation methods, including dry heat treatment, centrifugation, utilization of antimicrobial drugs and selective isolation media for actinomycete diversity analysis, and screening of the obtained We also perform antibacterial and antifungal activity analysis of the screened actinomycetes, isolate compounds from the target strains, and assist our clients in finding novel active natural products.

We Do Better

Lifeasible has optimized the experimental conditions, developed specific primers for Actinomyces and improved and optimized the sequence splicing procedure to improve the detection rate of Actinomyces. We provide comprehensive services on inter-rhizosphere biology, customizing comprehensive solutions for the isolation and identification of plant inter-rhizosphere actinomycetes, and various assays and histological analyses to meet all your needs in one stop.

*If your organization requires the signing of a confidentiality agreement, please contact us by email.

For research use only, not intended for any clinical use.

Related Services

• Inter-rhizosphere Microbiota Analysis
• Collection and Identification of Root Secretions
• Inter-rhizosphere Fungal Analysis
• Inter-rhizosphere Bacterial Analysis