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Epigenetic Analysis at the RNA Level
Plant gene expression is involved in various biological processes, including plant development and stress response. Epigenetic mechanisms such as DNA methylation, post-translational modification of histones, chromatin remodeling, and non-coding RNAs play essential roles in regulating plant gene expression. Increasing evidence suggests that these different epigenetic mechanisms are highly interconnected, leading to the complexity of transcriptional reprogramming during plant development and in response to environmental stress. Lifeasible can provide you with epigenetic analysis services at the RNA level from various aspects, including small RNAs, non-coding RNAs, and miRNAs.
We provide various research solutions by combining bioinformatics research tools to help you decipher the important role of miRNAs in regulating gene expression, cell cycle, and developmental timeline of organisms.
We help you obtain genome-wide small RNA profiles of species by constructing small RNA libraries and performing large-scale sequencing of small RNA libraries, which includes the mining of new small RNA molecules, prediction and identification of target genes, differential expression analysis between samples, small RNA clustering, and expression profiling.
Non-coding RNA gene identification
We offer customers direct marker identification and several technical solutions for large-scale searches for non-coding RNA genes. And we are constantly improving; our goal is to provide our customers with validated protocols for non-coding RNA gene identification.
Theoretical predictions of non-coding RNA genes
We provide a theory-based approach to finding non-coding RNA genes from the genome, which can be used as an initial screen to provide a large reservoir for experimental studies. The prediction and labeling of non-coding RNA genes provided by our is a combination of specific and universal methods.
In different plant tissues and organs and at different developmental periods, miRNA expression profiles and regulation are different. We offer a variety of methods for studying how miRNAs regulate plant tissue development. It can also be applied to the study of miRNA biological functions in a variety of plant species.
We provide customers with RNAi technology, which uses artificial methods to introduce silencing inducers into the host to degrade the transcripts of target genes. In addition to hpRNAi and VIGS, we also offer RNA silencing technologies such as co-repression and antisense repression, which can be used to varying degrees to meet your needs for suppressing gene expression.
We can provide the tools to further investigate RNA post-transcriptional modifications such as m6A, m5C, and Ψ, and provide technical support to enrich and improve RNA epigenetics.
Please feel free to contact us for more information on our solutions.
The services provided by Lifeasible cover all aspects of plant research, please contact us to find out how we can help you achieve the next research breakthrough.
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