Ribonucleic acid (RNA) is a polymeric single-stranded molecule that constitutes living cells alongside deoxyribonucleic acid (DNA) and protein. Long non-coding RNAs (lncRNAs) are broad and myriad groups of endogenous single-stranded polynucleotides non-protein coding transcript. The mechanism underlying the functions of lncRNAs is a captivating area of research. More and more studies have indicated that regulation of transcriptional, post-transcription processes and new insights into potential functions can be elucidated by lncRNAs binding with proteins.

Lifeasible provides analysis services for plant lncRNA-protein interactions to help our customers worldwide in plant science research. Our platform is equipped with cutting-edge facilities and professional experts to support research. Here, we provide various services according to customers’ demands.

Plant lncRNA as Guides for Recruiting Proteins

• First, lncRNAs can act as guide molecules to recruit proteins to the site of gene transcription, regulating gene expression. In addition to guiding proteins to target gene-specific sites and inhibiting target gene expression, lncRNAs can also serve as guide molecules for other functional proteins to participate in the regulation of target gene expression.
• We provide analysis services of plant lncRNA as guides for recruiting proteins. lncRNAs work by binding to proteins and modifying histones with H3K4me3, thereby maintaining the open state of chromatin and active transcription. In addition, lncRNA can also act as a guide molecule for nuclear inhomogeneous ribonucleoprotein-K, localizing it to the gene promoter region and activating transcriptional expression.

Fig. 1 Schematic representation of lncRNA-protein interactions.

Plant lncRNA as Scaffolds for Linking Multiple Proteins Together

• The lncRNA can also act as a scaffolding molecule for two or more proteins, combining these proteins into protein complexes.
• We help our customers analyze the role of plant lncRNAs as scaffolds linking multiple proteins. lncRNA directly binds to the genomic regions and functions as scaffold to link histone modification proteins.

Plant lncRNA as Decoys for Hijacking Proteins

• Finally, lncRNAs can also act as protein decoy molecules, tuning away proteins bound to the genome, thereby inhibiting gene transcription and expression.
• We help customers analyze plant lncRNAs’ role as decoys for hijacking proteins. lncRNAs interact with proteins, and their complexes are translocated in cells; some lncRNAs bind multiple splicing factors and dynamically regulate transcriptome diversity.

Our Technical Support

We provide advanced, high-quality, well-established technical support to help our customer’s study plant lncRNA-DNA interactions, including but not limited to in vitro RNA Pull-Down assay, PIP-Seq (protein interaction profile sequencing), TRAP-Seq (translating ribosome affinity purification), RIP-Seq (RNA immunoprecipitation), CLIP-Seq (cross-linking immunoprecipitation), ChIRP-MS (ChIRP followed by mass spectrometry), and others.

Lifeasible provides cost-effective, high-quality, and hassle-free services to our customers worldwide. ​We provide our clients with direct access to our experts and prompt responses to their questions. If you are interested in our services or have questions, please feel free to contact us or make an online inquiry.

*If your organization requires the signing of a confidentiality agreement, please contact us by email.

For research use only, not intended for any clinical use.

Related Services

• Plant lncRNA-miRNA Interactions Analysis
• Plant lncRNA-mRNA Interactions Analysis
• Plant lncRNA-DNA Interactions Analysis